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Best Disinfectant Sprays


Last Updated on August 13, 2020 by Josh Desair

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Last Updated on August 13, 2020 by Josh Desair

With the cold and flu season just around the corner, you need to get a leg up on the viruses that cause these illnesses. One of the best ways to protect yourself and your family is by investing in the proper cleaning supplies to have in your home and business. The right disinfectant sprays can kill the bacteria and viruses that will ultimately make you sick. If you or someone in your household were to get sick, these sprays can be used to disinfect the surfaces in your home so the illness won’t tear through your family like wildfire.

We’ve compiled a list of the ten best disinfectant sprays available to purchase today. Keep reading to find one that’s the best fit for your needs, whether you want to protect your family, your staff members, or your business.

10 Best Disinfectant Sprays in 2020

1. Ozium Air Sanitizer

Best Disinfectant Spray - Ozium

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First up on our list is this two-pack of Ozium Air Sanitizer. This product will help to clean the air that you’re breathing in your home and even eliminate offensive scents like cigarette smoke.

Air Sanitizer
This spray works by temporarily reducing the number of airborne bacteria in your space. It can also fight the spread of this bacteria to prevent it from reaching other areas of your home.

Goodbye Odors
Whether you’re dealing with the aforementioned cigarette smoke, cooking smells, or stinky bathrooms, this spray can make swift work of your smelly spaces.

Cost and Value
While the price is on the higher end of the spectrum, it’s important to note that you do receive two canisters for the price.


  • Smells nice
  • Eliminates odors fast
  • Easier to find than other disinfecting alternatives
  • Great customer service


  • Does not disinfect surfaces

2. CleanSmart Surface Cleaner

Best Disinfectant Spray - CleanSmart

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Next up is another two-pack of disinfectant. This product from CleanSmart is a great pick for daily surface cleaning. If you’re worried about bringing bugs and viruses into your home, you need something that’ll be able to disinfectant all the different surfaces in your space.

This spray is designed to kill 99.9% of viruses and bacteria without leaving any harsh residue in its wake. That means your countertops and various household surfaces should be safe from any harm when you use this product. We do always recommend doing a spot test beforehand though, just to be sure.

This spray is made using nature’s germ killer – hypochlorous. This acid is found naturally in the human body as it’s what your white blood cells produce to fight off any incoming infections.

Cost and Value
We were very surprised to see how affordable this two-pack of sprays is, especially considering its natural formulation.


  • Safe on most surfaces
  • Can be used every day
  • Doesn’t leave strong odors or fumes in its wake
  • Child and pet-friendly


  • Packing may leave something to be desired

3. Rmr-141 Fungicide

Best Disinfectant Spray - RMR-141

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If you’re looking for one of the strongest mold killers on the market, look no further than RMR’s 141 Ready to Use spray. This efficient product can inhibit the growth of both mold and mildew while also disinfecting the area you’re spraying.

This spray is one of the only EPA-registered disinfectants on the market. This simply means that it’s been rigorously tested and registered by health authorities around the world.

Goodbye Bacteria
This mildew, odor, and mold killing spray will also tackle 99.9% of all household bacteria. It’s also fungicidal and works well against many different types of bacteria.

Cost and Value
While the price does seem higher than some of the other options on our list, we think it’s more than worth the cost. You may want to consider purchasing a two-pack to save money.


  • All-in-one spray
  • Can be used residentially or commercially
  • Can kill 141+ different microorganisms
  • Makes quick work of mold and mildew


  • Doesn’t have the best scent

4. Clorox Clean-Up

Best Disinfectant Spray - Clorox Clean-Up with Bleach

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Clorox and bleach seem to be difficult products to get your hands on these days. That’s because they’re both high-quality disinfectants. The Clorox Clean-Up with Bleach is just about one of the best combinations you can have in your house to combat household bacteria and viruses.

Works Fast
One of the best features of this product is that it works very quickly. It can disinfect and kill 99.9% of household bacteria in just 30 seconds!

Smart Tube Technology
Have you ever spent your money on a household cleaning spray only to find that you’re unable to get every last drop out of the bottle? We’ve all tried tilting and tipping our bottles to try and squeeze the last few sprays out of our cleaners. Well, this cleaner from Clorox uses a new Smart Tube technology that reaches to the very bottle of the bottle allowing you to get every drop from your purchase.

Cost and Value
This two-pack is worth every last penny. You cannot go wrong with a household cleaner that is as effective and efficient as Clorox paired with bleach!


  • Can remove stains
  • Not as offensive smelling as other bleach products
  • Sanitizes surfaces
  • No need to rinse


  • Can dye your clothing

5. Spray Nine 26801

Best Disinfectant Spray - Spray Nine 26801

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If you’re searching for a heavy-duty cleaning solution that can also work as a degreaser and a disinfectant, look no further than this product from Spray Nine. Get rid of all the other cleaners under your cupboard and replace them with this one-gallon jug.

Professional Strength
You already know that this product can replace a lot of the cleaners you already have in your home. You might be interested in knowing that not only is it incredibly versatile, but it’s also professional-grade, too.

Works Fast
This EPA-registered cleaner can disinfect your surfaces in just 30 seconds to protect against several different viruses. Give it 45 seconds to kill a variety of different bacteria.

Cost and Value
We were surprised to see just how affordable this huge jug of cleaner is. Its affordable price tag paired with its high-quality concentration makes it a perfect pick for most households.


  • Versatile
  • Ready to use
  • Contains no petroleum
  • EPA and NSF approved


  • May not work as well as a degreaser

6. Parker W60697SM

Best Disinfectant Spray - Parker W60697SM

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This hospital-grade disinfectant has been approved for use against a variety of different viruses like the H1N1 influenza A virus and pathogens like MRSA.

No Offensive Odors
Other disinfectants on the market may be efficient at their job, but they often come with an unfortunate side effect – an ungodly stench. Thankfully, this particular disinfectant doesn’t have an offensive odor at all.

One Step
This cleaner is very easy-to-use. You simply spray it on the surface you wish to disinfectant and let the product do its magic.

Cost and Value
This is one of the most affordable options in our buying guide. We loved its hospital-grade quality as it provides the peace of mind we all need in these uncertain times.


  • Non-abrasive
  • Easy-to-use
  • Great on nonporous surfaces
  • Affordable


  • Cannot purchase in Europe or Canada

7. Clorox Healthcare Fuzion

Best Disinfectant Spray - Clorox Healthcare

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Clorox is really pulling out all the stops when it comes to providing products for disinfecting purposes. This Fuzion cleaner is usable on a variety of surfaces and contains bleach so you know it’s going to disinfect quickly.

Goodbye Germs
This solution is designed to kill 52 different types of bacteria, fungi, and viruses. You only need to leave the solution on the desired surfaces for one minute to begin reaping its benefits.

Fast Kill Time
This powerful spray can kill C. difficile spores in just two minutes, one o the fastest kill times available at the time of writing.

Cost and Value
This product is affordably priced, considering how effective it is at killing viruses and bacteria. We love that Clorox is focusing on creating products specifically for healthcare facilities, too, as we all know how important cleanliness and sanitization protocols are for these facilities.


  • One-step
  • Efficient
  • No strong scent
  • Less harsh than bleach alone


  • Some issues with the sprayer not spraying

8. Nisus Dsv

Best Disinfectant Spray - Nisus DSV

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While this product technically isn’t a spray as it arrives in a jug, it’s designed to be used as one. Simply pour it into your favorite spray bottle and have the power of this strong disinfectant at your fingertips.

Kills Viruses
This product is designed to kill hantavirus, E.coli, staph, strep, and even viruses that we’re dealing with today on a global scale . It can also make quick work out of a variety of different bacteria, too.

64 Gallons of Solution
Since this product is highly concentrated, you can expect to get around 64 gallons of product out of this one gallon of concentrate.

Cost and Value
Given its powerful punch, we think Nisus DSV is more than worth the investment. Sixty-four gallons of disinfectant will last you a very long time, providing you with a lot of bang for your buck.


  • Lasts a long time
  • Can be used residentially or commercially
  • Easy to use
  • Can be used to deal with wildlife infestations/smells


  • Should be used in well-ventilated areas only

9. Diamond Disinfectant 1000

Best Disinfectant Spray - Diamond Disinfectant 1000

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Here’s another product that’s technically not a spray yet, but is designed to be used as one. This 1-gallon jug is highly concentrated and will make 160 gallons of disinfectant in total.

For Commercial or Residential Use
If you own a restaurant, hotel, or gym, you’re going to need a heavy-duty disinfectant to keep things safe for your patrons these days. This EPA-registered product is a perfect pick to add to your cleaning arsenal. If you don’t own a commercial business, you can still benefit from purchasing this for use in your home. It’s a great option if you have someone in your household who works in one of the aforementioned industries or even if they work at the hospital.

Multi-Surface Cleaning
This disinfectant is designed for use on a variety of different surfaces. Use it on your floors, countertops, bathtub, toilets, trash cans, or pretty much anywhere high-contact surface in your business or home.

Cost and Value
While the price may seem high initially, remember that this solution is highly concentrated. It would be difficult to find 160 gallons of cleaner for this price.


  • Pleasant scent
  • Effective against many viruses
  • Lasts a long time
  • Efficient


  • Cannot be used directly on electronics

10. Purefypro

Best Disinfectant Spray - Purefypro Disinfectant Spray

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The last product in our list of sprays is this high-quality option from Purefy. It’s designed to kill bugs like MRSA, VRE, norovirus, and even the influenza virus in as little as 60 seconds.

Pure Construction
This spray is made without using any alcohol, synthetic fragrances, and VOC. There’s absolutely no chemical residue leftover once you use it, either.

Safe for Use
It’s non-corrosive and safe for use on materials that other sprays cannot be used on like gym mats. If you or someone in your household has allergies or asthma and is sensitive to other sprays on the market, you should find that this product won’t cause any irritations.

Cost and Value
When you purchase this product, you’re receiving one 16-oz bottle and two travel-sized bottles (at 1.7 oz each). We loved that the manufacturer includes travel-sized bottles to keep in your luggage or in your vehicle during the cold and flu season.


  • Pleasant scent
  • Not sticky
  • Spray or stream option on the nozzle
  • Travel-sized bottles perfect for on-the-go disinfecting
  • Safe for use around children


  • Higher price tag

Our Conclusion

It seems more important now than ever to protect yourself and your family members with the right household cleaners. If you’re hoping to stave off any colds, flu, or viruses this year, you need disinfectant sprays in your cleaning arsenal.

The ten above options are the best that are currently available on the market. Take your pick from any of them and you’ll find you have the best defense against contracting any virus this year.

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